600-401-EC2
RRAS2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-EC2
- Zusätzliche Namen:
- RRAS2|RRAS2 Antibody, TC21, TC21, Ras-related protein R-Ras2, Ras-like protein TC21
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti- RRAS2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human RRAS2.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P62070
- Synonyme:
- NS12;ras-like protein TC21;ras-related protein R-Ras2;related RAS viral (r-ras) oncogene homolog 2;TC21;teratocarcinoma oncogene
- Weitere Details:
- Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
- Versandbedingungen:
- Dry Ice