600-401-DU7
PTK7 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-DU7
- Zusätzliche Namen:
- PTK7|PTK7 Antibody, CCK4, CCK-4, CCK4, Inactive tyrosine-protein kinase 7, Colon carcinoma kinase 4
- Anwendung:
- ELISA, IHC, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-PTK7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the N-terminus of human PTK7.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q13308
- Synonyme:
- CCK-4;CCK4;colon carcinoma kinase 4;inactive tyrosine-protein kinase 7;Protein-tyrosine kinase 7;pseudo tyrosine kinase receptor 7;PTK7 protein tyrosine kinase 7;tyrosine-protein kinase-like 7
- Weitere Details:
- Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
- Versandbedingungen:
- Dry Ice