600-401-DC3
NKX2-2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-DC3
- Zusätzliche Namen:
- NKX2-2|NKX2-2 Antibody, NKX2B, NKX2.2, NKX2B, Homeobox protein NK-2 homolog B
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-NKX2-2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the internal region of human NKX2-2.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O95096
- Synonyme:
- homeobox protein NK-2 homolog B;homeobox protein Nkx-2.2;NK2 transcription factor related, locus 2;NK2 transcription factor-like protein B;NKX2.2;NKX2B
- Weitere Details:
- NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature a-, b- and PP cells, and in NKX2-2-null mice embryos, all b-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.
- Versandbedingungen:
- Dry Ice