600-401-D96
NMDA R2C phospho S1244 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-D96
- Zusätzliche Namen:
- Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C|Grin2c
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Rat
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- Immunogen:
- Anti-NMDA R2C pS1244 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244.
- Formulierung:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Uniprot:
- Q00961
- Synonyme:
- GluN2C;glutamate [NMDA] receptor subunit epsilon-3;glutamate receptor ionotropic, NMDA 2C;glutamate receptor, ionotropic, N-methyl D-aspartate 2C;glutamate receptor, ionotropic, NMDA2C;N-methyl D-aspartate receptor subtype 2C;NMDA glutamate receptor;NMDAR2C;NR2C
- Weitere Details:
- NMDA R2C pS1244 Antibody detects phosphorylated NMDA R2C protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Phosphorylation of Ser1244 has been shown to regulate NMDA receptor channel function. Anti-NMDA R2C pS1244 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.
- Versandbedingungen:
- Dry Ice