NMDA R2A phospho Y1325 Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: 600-401-D90
Zusätzliche Namen:: Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a|Grin2a
Anwendung:: WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Rat
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: 0.01 M HEPES, 0.15 M Sodium Chloride
Immunogen:: Anti-NMDA R2A pY1325 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1325.
Formulierung:: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Uniprot:: Q00959
Synonyme:: GluN2A;glutamate [NMDA] receptor subunit epsilon-1;glutamate receptor ionotropic, NMDA 2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A;N-methyl D-aspartate receptor subtype 2A;N-methyl-D-aspartate receptor subunit 2A;NMDAR2A;NR2A
Weitere Details:: NMDA R2A pY1325 Antibody detects NMDA R2A protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. Channels with physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Recently, phosphorylation of Tyrosine 1325 of the NR2A subunit has been shown to be increased in human brain tissue sections from HIV-infected individuals with encephalitis. In addition, Tyr1325 phosphorylation has been linked with depression-related behavior. Anti-NMDA R2A pY1325 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.

Versandbedingungen:: Dry Ice