600-401-CU6
MINA Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-CU6
- Zusätzliche Namen:
- Ribosomal oxygenase 2, 60S ribosomal protein L27a histidine hydroxylase, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA (EC:1.14.11.-), Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, RIOX2, MDIG, MINA, MINA53, NO52|RIOX2
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-MINA antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human MINA.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q8IUF8
- Synonyme:
- 60S ribosomal protein L27a histidine hydroxylase;bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA;histone lysine demethylase MINA;JMJD10;MDIG;MINA;MINA53;mineral dust induced gene protein;Mineral dust-induced gene protein;MYC induced nuclear antigen;MYC-induced nuclear antigen;MYC-induced nuclear antigen 53;myc-induced nuclear antigen, 53 kDa;NO52;nucleolar protein 52;ribosomal oxygenase 2;ribosomal oxygenase MINA;ROX
- Weitere Details:
- MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.
- Versandbedingungen:
- Dry Ice