600-401-CM7
LRRFIP1 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-CM7
- Zusätzliche Namen:
- LRRFIP1|LRRFIP1 Antibody, GCF2, TRIP, FLAP1, GCF-2, FLAP-1, HUFI-1, FLIIAP1, GCF2, Leucine-rich repeat flightless-interacting protein 1, GC-binding factor 2, LRR FLII-interacting protein 1
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-LRRFIP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the C-terminus of human LRRFIP1.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q32MZ4
- Synonyme:
- FLAP-1;FLAP1;FLIIAP1;GC-binding factor 2;GCF-2;GCF2;HUFI-1;leucine rich repeat (in FLII) interacting protein 1;leucine-rich repeat flightless-interacting protein 1;LRR FLII-interacting protein 1;NEDD8-conjugating enzyme;TAR RNA-interacting protein;TRIP
- Weitere Details:
- LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway.
- Versandbedingungen:
- Dry Ice