600-401-C02
STIM1 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-C02
- Zusätzliche Namen:
- STIM1|STIM1, Stromal interaction molecule 1, GOK
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- STIM1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide near the c-terminus of human STIM1.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q13586
- Synonyme:
- D11S4896E;GOK;IMD10;STRMK;stromal interaction molecule 1;TAM;TAM1
- Weitere Details:
- In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. Anti-STIM1 antibody is ideal for investigators involved in enzyme research.
- Versandbedingungen:
- Dry Ice