FAIM2 Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: 600-401-BD1
Zusätzliche Namen:: FAIM2|FAIM2 Antibody, LFG, LFG2, NGP35, NMP35, TMBIM2, KIAA0950, LFG, Protein lifeguard 2, Fas apoptotic inhibitory molecule 2
Anwendung:: ELISA, IHC, WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Lagerbedingungen:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Rockland Inc
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-FAIM2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the N-terminus of human FAIM2.
Formulierung:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: Q9BWQ8
Synonyme:: Fas apoptotic inhibitory molecule 2;LFG;LFG2;neural membrane protein 35;NGP35;NMP35;protein lifeguard 2;TMBIM2;transmembrane BAX inhibitor motif-containing protein 2
Weitere Details:: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.

Versandbedingungen:: Dry Ice