600-401-BB5
ERAP1 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-BB5
- Zusätzliche Namen:
- ERAP1|ERAP1 Antibody , ALAP, A-LAP, ARTS1, ERAAP, APPILS, ARTS-1, ERAAP1, PILSAP, PILS-AP, KIAA0525, UNQ584/PRO1154, Endoplasmic reticulum aminopeptidase 1
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-ERAP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human ERAP.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9NZ08
- Synonyme:
- A-LAP;adipocyte-derived leucine aminopeptidase;ALAP;aminopeptidase PILS;aminopeptidase regulator of TNFR1 shedding;APPILS;ARTS-1;ARTS1;CTD-2260A17.2;endoplasmic reticulum aminopeptidase 1;endoplasmic reticulum aminopeptidase associated with antigen processing;ERAAP;ERAAP1;PILS-AP;PILSAP;puromycin-insensitive leucyl-specific aminopeptidase;type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
- Weitere Details:
- The endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1), a member of the peptidase M1 family, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). It is also designated as adipocyte-derived leucine aminopeptidase (A-LAP), puromycin-insensitive leucine-specific aminopeptidase (PILS-AP) and aminopeptidase regulator of TNFR1 shedding (ARTS-1) (3). ERAP1 is localized to the lumen of the ER and induced by interferon. It may be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (3,4).
- Versandbedingungen:
- Dry Ice