600-401-BB4
EPM2A Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-BB4
- Zusätzliche Namen:
- EPM2A|EPM2A Antibody, EPM2, MELF, Laforin, Lafora PTPase, LAFPTPase
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-EPM2A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human EPM2A.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O95278
- Synonyme:
- epilepsy, progressive myoclonus type 2, Lafora disease (laforin);epilepsy, progressive myoclonus type 2A, Lafora disease (laforin);EPM2;EPM2A, laforin glucan phosphatase;glucan phosphatase;glycogen phosphatase;lafora PTPase;laforin;LAFPTPase;MELF
- Weitere Details:
- The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
- Versandbedingungen:
- Dry Ice