600-401-AY1
DTX4 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-AY1
- Zusätzliche Namen:
- Deltex 4 E3 ubiquitin ligase, RNF155|DTX4
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-DTX4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the internal region of human DTX4.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9Y2E6
- Synonyme:
- deltex 4 homolog;deltex 4, E3 ubiquitin ligase;deltex homolog 4;deltex4;E3 ubiquitin-protein ligase DTX4;protein deltex-4;RING finger protein 155;RING-type E3 ubiquitin transferase DTX4;RNF155
- Weitere Details:
- The Deltex 4 E3 ubiquitin ligase (DTX4) is a member of a protein family that is involved in Notch signaling and neurogenesis (1). Recent studies have shown that DTX4 is also associated with the innate immune response (2). Following the activation of type I interferon signaling, the Nod-like receptor protein 4 (NLRP4) recruits DTX4 for Lys48-linked polyubiquitination and degradation of the kinase TBK1 (NAK), thereby maintaining immune homeostasis during antiviral innate immunity (2).
- Versandbedingungen:
- Dry Ice