600-401-AS4
DAP Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-AS4
- Zusätzliche Namen:
- DAP|DAP Antibody, DAP1, Death-associated protein 1, DAP-1
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-DAP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human DAP.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- P51397
- Synonyme:
- DAP-1;death-associated protein 1
- Weitere Details:
- The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
- Versandbedingungen:
- Dry Ice