600-401-AM1
CMPK2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-AM1
- Zusätzliche Namen:
- CMPK2|CMPK2 Antibody, TYKi, TMPK2, UMP-CMPK2, UMP-CMP kinase 2, mitochondrial, Nucleoside-diphosphate kinase
- Anwendung:
- ELISA, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-CMPK2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the C-terminus of human CMPK2.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q5EBM0
- Synonyme:
- cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial;cytidylate kinase 2;mitochondrial UMP-CMP kinase;NDK;nucleoside-diphosphate kinase;thymidine monophosphate kinase 2;thymidylate kinase family LPS-inducible member;TMPK2;TYKi;UMP-CMP kinase 2, mitochondrial;UMP-CMPK2;UMP/CMP kinase
- Weitere Details:
- UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
- Versandbedingungen:
- Dry Ice