600-401-AK3
CIDE-A Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-AK3
- Zusätzliche Namen:
- CIDE-A Antibody, CIDE-A, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A|CIDEA
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-CIDE-A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid peptide near the C-terminus of human CIDE-A.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O60543
- Synonyme:
- cell death activator CIDE-A;Cell death-inducing DFFA-like effector A;CIDE-A
- Weitere Details:
- Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.
- Versandbedingungen:
- Dry Ice