600-401-A40S
NCOA3 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-A40S
- Zusätzliche Namen:
- NCOA3|rabbit anti-NCOA3 antibody, NCOA 3, NCOA-3, Nuclear receptor coactivator 3 NCoA-3, Thyroid hormone receptor activator molecule 1, TRAM-1, pCIP, bHLHe42, Receptor-associated coactivator 3, RAC-3, Amplified in breast cancer 1 protein, AIB-1, Steroid receptor coactivator protein 3, SRC-3, ACTR, AIB1, BHLHE42, RAC3, TRAM1
- Anwendung:
- ELISA, IHC, WB, IP
- Konzentration:
- 0.82 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C diluted. Avoid freeze/thaw cycles., See Manual Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human NCOA3 isoform a protein.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q9Y6Q9
- Synonyme:
- ACTR;AIB-1;AIB1;amplified in breast cancer 1 protein;bHLHe42;CAGH16;CBP-interacting protein;class E basic helix-loop-helix protein 42;CTG26;KAT13B;nuclear receptor coactivator 3;pCIP;RAC3;receptor-associated coactivator 3;SRC-3;SRC3;steroid receptor coactivator protein 3;thyroid hormone receptor activator molecule 1;TNRC14;TNRC16;TRAM-1
- Weitere Details:
- This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). NCOA3 is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. NCOA3 may be associated with diseases such as breast cancer and meningothelial meningioma. Anti-NCOA3 Antibody is useful for researchers interested in cancer research, chromatin binding, transcription coactivator activity, Immunology, and Nuclear Signaling research.
- Versandbedingungen:
- Dry Ice