600-401-947
Aubergine/Sting Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-947
- Zusätzliche Namen:
- aub|rabbit anti-Aubergine/Sting Antibody, rabbit anti-Aubergine Antibody, rabbit anti-Sting Antibody, Aubergine isoform A
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Insect/Arthropod
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Insect/Arthropod
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Drosophila melanogaster Aubergine/Sting protein.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- O76922
- Synonyme:
- Aub;aub-PA;aub-PC;aubergine;CG6137;CG6137-PA;CG6137-PC;Dmel_CG6137;Dmel\CG6137;ms(2)32D;Protein sting;stellate-interacting gene;sti;sting
- Weitere Details:
- Aubergine (Sting) is a Drosophila protein involved in germ-line development and RNA interference. Drosophila melanogaster has a robust and efficient innate immune system, which reacts to infections ranging from bacteria to fungi and, as discovered recently, viruses as well. The known Drosophila immune responses rely on humoral and cellular activities, similar to those found in the innate immune system of other animals. Recently, RNAi or 'RNA silencing' has arisen as a possible means by which Drosophila can react to specific pathogens, transposons and retroviral elements, in a fashion similar to that of a traditional mammalian adaptive immune system instead of in a more generalized and genome encoded innate immune-based response. RNAi is a highly conserved regulation and defense mechanism, which suppresses gene expression via targeted RNA degradation directed by either exogenous dsRNA (cleaved into siRNAs) or endogenous miRNAs. In plants, RNAi has been found to act as an antiviral immune response system. In Drosophila multiple core RNAi pathway genes have been reported, including piwi, vasa intronic gene (vig), aubergine (aub), armitage (armi), Rm62, r2d2 and Argonaute2 (AGO2).
- Versandbedingungen:
- Dry Ice