600-401-922
MCM2 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 600-401-922
- Zusätzliche Namen:
- MCM2|rabbit anti-MCM2 antibody, MCM-2, BM28, CCNL1, CDCL1, Minichromosome maintenance complex component 2, Nuclear protein BM28, DNA replication licensing factor MCM2
- Anwendung:
- ELISA, WB
- Konzentration:
- 0.98 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an N-Terminal region near amino acids 15-40 of human MCM2 protein.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- P49736
- Synonyme:
- BM28;CCNL1;cdc19;CDCL1;cell devision cycle-like 1;cyclin-like 1;D3S3194;DFNA70;DNA replication licensing factor MCM2;minichromosome maintenance deficient 2 (mitotin);minichromosome maintenance protein 2 homolog;MITOTIN;nuclear protein BM28
- Weitere Details:
- This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by protein kinases CDC2 and CDC7. Double serines at positions 26 and 27 are conserved in rat and mouse. High homology >88% to similar proteins from several other species. Expected broad reactivity to various lysates.
- Versandbedingungen:
- Dry Ice