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  2. Polyclonal

202-401-B95

IL-2 Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
202-401-B95
Zusätzliche Namen:
IL2|rabbit anti-Interleukin-2, rabbit anti-IL-2 antibody, IL2, T-cell growth factor, TCGF, Aldesleukin, Lymphokine
Anwendung:
ELISA, WB
Konzentration:
1 mg/ml
Physischer Zustand:
Lyophilized
Spezies-Reaktivität:
Feline
Lagerbedingungen:
2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Hersteller:
Rockland Inc
Host:
Rabbit
Reaktivitäten:
Feline
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to 134 amino acids of mature cat IL-2.
Formulierung:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Uniprot:
Q07885
Synonyme:
IL-2;interleukin-2;T-cell growth factor;TCGF
Weitere Details:
IL-2 is a member of a family of cytokines, which also includes IL-4, IL-7, IL-9, IL-15 and IL-21. All members of this family signal through a receptor complex that includes the common gamma chain. IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor alpha (CD25), IL-2 receptor beta (CD122) and the common gamma chain. The main function of IL-2 is to promote the development of T regulatory cells. IL-2 is produced by several cell types including, B cells, gamma-delta T cells, CD4+ T cells, CD8+ T cells, and eosinophils. It has been found to be similar to IL-15 in terms of function. Both IL-2 and IL-15 are able to facilitate production of immunoglobulins made by B cells and induce the differentiation and proliferation of natural killer cells. The primary differences between IL-2 and IL-15 are found in adaptive immune responses: IL-2 participates in maintenance of T-Regs and reduces self-reactive T cells while IL-15 is necessary for maintaining highly specific T cell responses by supporting survival of CD8 memory T cells.
Versandbedingungen:
Ambient