200-B08-N89
CD80 Phycoerythrin Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-B08-N89
- Zusätzliche Namen:
- Cd80|T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80, Cd80
- Anwendung:
- Flow Cytometry, IHC, IF, IP
- Konzentration:
- 0.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- 2-8[o]C unopened. Protect from light.
- Hersteller:
- Rockland Inc
- Host:
- Hamster
- Reaktivitäten:
- Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Klon:
- 16-10A1
- Uniprot:
- Q00609
- Synonyme:
- activation B7-1 antigen;B7 protein;B71;Cd28;Cd28l;Ly-5;Ly-53;Ly5;Ly53;MIC17;T-lymphocyte activation antigen CD80;TSA1
- Weitere Details:
- Anti-CD80 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
- Versandbedingungen:
- Blue Ice