200-B08-M69
CD3e Phycoerythrin Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-B08-M69
- Zusätzliche Namen:
- Cd3e|T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e
- Anwendung:
- Flow Cytometry
- Konzentration:
- 0.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Lagerbedingungen:
- 2-8[o]C unopened. Protect from light.
- Hersteller:
- Rockland Inc
- Host:
- Hamster
- Reaktivitäten:
- Mouse
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- Anti-CD3 Antibody (Monoclonal) was produced by repeated immunizations with H-2Kb specific cytotoxic T lymphocyte clone BM10-37.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Klon:
- 145-2c11
- Uniprot:
- P22646
- Synonyme:
- AI504783;CD3;CD3epsilon;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell surface glycoprotein CD3 epsilon chain;T3e
- Weitere Details:
- CD3 is a multi-subunit complex consisting of 4 different invariable membrane proteins, CD3E, CD3D, CD3G and CD3-omega. These CD3 proteins are expressed on the surface of T-cells and Thymocytes during thymocyte development. They are non-covalently associated with the TCR heterodimer and form the functional TCR-CD3 antigen receptor complex of the T-lymphocyte. CD3 expression is significant during Intrathymic T-lymphocyte maturation, TCR signaling and Thymocyte differentiation. Stimulation of TCR-CD3 complex results in activation of various protein tyrosine kinases including ZAP-70 affecting multiple cellular responses including T-cell proliferation, clonal expansion, induction of tolerance and apoptosis. Mutations in the sub-unit chains of CD3 have been associated with various immunodeficiency syndromes including SCID.
- Versandbedingungen:
- Blue Ice