200-401-H10
PERP Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-401-H10
- Zusätzliche Namen:
- p53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW, PERP, KCP1, KRTCAP1, PIGPC1, THW|PERP
- Anwendung:
- ELISA, IHC, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- PERP Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to amino acids near the c-terminus of human PERP, which differ from the mouse sequence by three amino acids.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- Q96A56
- Synonyme:
- p53-dependent damage-inducible nuclear protein 1;p53-inducible p53DINP1;p53DINP1;SIP;stress-induced protein;Teap;TP53DINP1;TP53INP1A;TP53INP1B;tumor protein p53-inducible nuclear protein 1
- Weitere Details:
- PERP antibody detects human PERP. The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family. Anti-PERP antibodies are ideal for investigators involved in Apoptosis research.
- Versandbedingungen:
- Dry Ice