Mcl-1 Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: 200-401-CS0
Zusätzliche Namen:: Mcl-1 Antibody, TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3|MCL1
Anwendung:: ELISA, IHC, WB, IF
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Lagerbedingungen:: -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Hersteller:: Rockland Inc
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
Immunogen:: Anti-Mcl-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids near the amino-terminus of human Mcl-1.
Formulierung:: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Uniprot:: Q07820
Synonyme:: bcl-2-like protein 3;bcl-2-related protein EAT/mcl1;BCL2 family apoptosis regulator;bcl2-L-3;BCL2L3;EAT;induced myeloid leukemia cell differentiation protein Mcl-1;Mcl-1;MCL1-ES;MCL1, BCL2 family apoptosis regulator;mcl1/EAT;MCL1L;MCL1S;myeloid cell leukemia 1;myeloid cell leukemia ES;myeloid cell leukemia sequence 1 (BCL2-related);TM
Weitere Details:: Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least three distinct isoforms designated Mcl-1L, Mcl-1S and Mcl-1ES. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death.

Versandbedingungen:: Dry Ice