200-401-C15S
OspB Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-401-C15S
- Zusätzliche Namen:
- ospB|rabbit anti-OspB Antibody, Outer surface protein B, Borrelia burgdorferi OspB, locus BB_A16
- Anwendung:
- ELISA, WB
- Konzentration:
- 1.1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Bacteria
- Lagerbedingungen:
- -20[o]C diluted. Avoid freeze/thaw cycles., See Manual Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Bacteria
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- MBP-fusion protein corresponding to Borrelia burgdorferi OspB protein.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- P17739
- Synonyme:
- BB_A16;BB_RS05185;outer surface lipoprotein OspB
- Weitere Details:
- OspB, is one of the major Outer Surface Proteins of the outer membrane of Borrelia burgdorferi, which is composed of various unique outer surface proteins (Osp) that have been characterized (OspA through OspF). The Osp proteins are lipoproteins anchored by N-terminally attached fatty acid molecules to the membrane. They are presumed to play a role in virulence, transmission, or survival in the tick. Two of the major surface Ag of Borrelia burgdorferi, the 31-kDa OspA and 34-kDa OspB proteins, show a high degree of sequence similarity, are encoded by a 49-kb plasmid and share a common promoter, and are coordinately transcribed. OspA, OspB, and OspD are expressed by B. burgdorferi residing in the gut of unfed ticks, suggesting that they promote the persistence of the spirochete in ticks between blood meals. OspB has a contributing role in the adherence of B. burgdorferi to the tick gut. B. burgdorferi has the ability to vary its surface proteins in response to immune attack.
- Versandbedingungen:
- Dry Ice