200-401-AX6
DR6 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-401-AX6
- Zusätzliche Namen:
- DR6 Antibody, DR6, CD358, BM-018, DR6, UNQ437/PRO868, Tumor necrosis factor receptor superfamily member 21, Death receptor 6|TNFRSF21
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-DR6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the N-terminus of human DR6.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- O75509
- Synonyme:
- BM-018;CD358;death receptor 6;DR6;TNFR-related death receptor 6;tumor necrosis factor receptor superfamily member 21
- Weitere Details:
- Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified.
- Versandbedingungen:
- Dry Ice