200-401-AX3
DR3 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-401-AX3
- Zusätzliche Namen:
- DR3 Antibody, DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, WSL-LR, TNFRSF12, APO3, DR3, WSL, WSL1, UNQ455/PRO779, Tumor necrosis factor receptor superfamily member 25, Apo-3|TNFRSF25
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- ABP:
- No Import Docs
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- Immunogen:
- Anti-DR3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids in extracellular domain of human DR3 precursor.
- Formulierung:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Uniprot:
- Q93038
- Synonyme:
- APO-3;apoptosis inducing receptor;apoptosis-inducing receptor AIR;apoptosis-mediating receptor DR3;apoptosis-mediating receptor TRAMP;DDR3;death domain receptor 3 soluble form;Death receptor 3;death receptor beta;DR3;GEF720;Guanine nucleotide exchange factor 720;LARD;lymphocyte-associated receptor of death;PH domain-containing family G member 5;Pleckstrin homology domain-containing family G member 5;PLEKHG5;Protein WSL;protein WSL-1;TNFRSF12;TR3;TRAMP;tumor necrosis factor receptor superfamily member 25;tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein);WSL-1;WSL-LR
- Weitere Details:
- Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kB activation.
- Versandbedingungen:
- Dry Ice