200-401-983
FLIP Alpha Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-401-983
- Zusätzliche Namen:
- c FLIP antibody, c FLIPL antibody, c FLIPR antibody, c FLIPS antibody, CASH antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator precursor antibody, CASP8 antibody, CASP8AP1 antibody, FLIP-L; CLARP1; MRIT alpha-1; CASH alpha; I-FLICE 1; FLAME-1 gamma|CFLAR
- Anwendung:
- ELISA, IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- FLIP Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of the human FLIPA Alpha/FLIPL protein.
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Uniprot:
- O15519
- Synonyme:
- c-FLIP;c-FLIPL;c-FLIPR;c-FLIPS;CASH;CASP8 and FADD-like apoptosis regulator;CASP8AP1;caspase homolog;caspase-eight-related protein;caspase-like apoptosis regulatory protein;caspase-related inducer of apoptosis;Casper;cellular FLICE-like inhibitory protein;cFLIP;CLARP;FADD-like antiapoptotic molecule 1;FLAME;FLAME-1;FLAME1;FLIP;I-FLICE;inhibitor of FLICE;MACH-related inducer of toxicity;MRIT;testis secretory sperm-binding protein Li 233m;Usurpin;usurpin beta
- Weitere Details:
- Apoptosis is related to many diseases and is induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors. Four splice variants of FLIPs have been identified and termed FLIP A Alpha, B Beta, G Gamma, and D Delta, respectively. Anti-FLIP antibody is ideal for investigators involved in Apoptosis, Cytokines and Growth factor research.
- Versandbedingungen:
- Dry Ice