Skip to content

Datenblatt ansehen

open_in_new
  1. Alles ansehen
  2. Monoclonal

200-301-W55

GFAP Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
200-301-W55
Zusätzliche Namen:
GFAP|Glial fibrillary acidic protein, Intermediate filament protein, Astrocyte, gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, GFAP antibody
Anwendung:
IHC, WB, IF
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Lagerbedingungen:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Hersteller:
Rockland Inc
Host:
Mouse
Reaktivitäten:
Human, Mouse, Rat
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:
Anti-GFAP Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to amino acids 411-422 (KTVEMRDGEVIK) of human GFAP.
Formulierung:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Klon:
S206A-8
Uniprot:
P14136
Synonyme:
ALXDRD;glial fibrillary acidic protein
Weitere Details:
The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. Anti-GFAP is ideal for investigators involved in Neuroscience Research, including Alexander Disease, Oligodendroglioma, Cytoskleton Remolding Neurofilaments and PIP3/AKT Signaling.
Versandbedingungen:
Dry Ice