200-301-E58
Hsp40 (YDJ1) Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 200-301-E58
- Zusätzliche Namen:
- Mitochondrial protein import protein MAS5, Yeast dnaJ protein 1, YDJ1, MAS5, YNL064C, N2418, YNL2418C|YDJ1
- Anwendung:
- ELISA, WB, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Yeast/Fungi
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Mouse
- Reaktivitäten:
- Yeast
- Immunogen:
- Hsp40 (YDJ1) Antibody was produced in mice by repeated immunizations raised against full length protein yeast Hsp40 (YDJ1).
- Klon:
- 1G10.H8
- Uniprot:
- P25491
- Synonyme:
- HSP40;MAB3;MAS5;type I HSP40 co-chaperone YDJ1;Yeast dnaJ protein 1;YNL064C
- Weitere Details:
- Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of Hsp40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not. Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. Hsp40 stimulates the ATPase activity of Hsp70 which in turn causes conformational changes of the unfolded proteins. The Hsp40-Hsp70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1.
- Versandbedingungen:
- Dry Ice