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  2. Monoclonal

200-301-901

CENP-E

Eine Lieferung in diese Region ist nicht möglich.

SKU:
200-301-901
Zusätzliche Namen:
CENPE|mouse anti-CENP-E antibody, Centromere-associated protein E, Centromeric protein E antibody, KIF10 antibody, Kinesin-7, Kinesin family member 10 antibody, Kinesin-related protein CENPE
Anwendung:
ELISA, WB, IF, IP
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Lagerbedingungen:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Hersteller:
Rockland Inc
Host:
Mouse
Reaktivitäten:
Human
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:
This protein A purified monoclonal antibody was produced by repeated immunizations with a full length recombinant protein corresponding to human CENP-E protein.
Formulierung:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Klon:
1H12
Uniprot:
Q02224
Synonyme:
CENP-E;Centromere autoantigen E (312kD);Centromere protein E;centromere protein E, 312kDa;centromere-associated protein E;KIF10;kinesin family member 10;kinesin-7;kinesin-related protein CENPE;MCPH13;PPP1R61;protein phosphatase 1, regulatory subunit 61
Weitere Details:
CENP-E, Centrosome-associated protein E, is a kinesin-like minus-end directed microtubule motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENP-E is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. CENP-E interacts with CENP-F and BUBR1 kinase. CENP-E associates with kinetochores during congression, relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.
Versandbedingungen:
Dry Ice