100-4167CP
IKB alpha C-terminal Peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 100-4167CP
- Zusätzliche Namen:
- NF-kappa-B inhibitor alpha peptide, I-kappa-B-alpha antibody, IkB-alpha, IkappaBalpha, IKBA, MAD3, NFKBI, control peptide, blocking peptide
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Reinheit:
- >95%
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Spezies:
- Human
- Weitere Details:
- Intended for use as a control peptide when used with anti-IKB alpha C-terminal specific to block specific interaction of anti-IKB alpha C-terminal specific [p/n 100-4167C] with the IKB alpha subunit. I-kappa-B-alpha inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, IKBA becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
- Versandbedingungen:
- Dry Ice