100-401-E00
Neuron specific enolase (NSE) Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 100-401-E00
- Zusätzliche Namen:
- ENO2|Gamma-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, NSE
- Anwendung:
- IHC, WB, IF
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Bovine, Human, Mouse, Rat
- Immunogen:
- Anti-NSE Antibody was produced by repeated immunizations with recombinant human NSE expressed in E. coli.
- Format:
- Antiserum
- Uniprot:
- P09104
- Synonyme:
- 2-phospho-D-glycerate hydro-lyase;2-phospho-D-glycerate hydrolyase;Enolase 2;enolase 2 (gamma, neuronal);epididymis secretory protein Li 279;gamma-enolase;HEL-S-279;neural enolase;neuron specific gamma enolase;neuron-specific enolase;neuronal enriched enolase;neurone-specific enolase;NSE
- Weitere Details:
- NSE antibody detects NSE protein. Neuron specific enolase (NSE) is an enzyme which catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway, and also the reverse reaction in gluconeogenesis. It is one of three mammalian enolases, which are also known as ENO1, ENO2, and ENO3 or alternately as enolase alpha, beta and gamma. The three enolases have different cell type specific expression patterns, so that antibodies to them are useful cell type specific markers. NSE corresponds to ENO2 or enolase gamma and is heavily expressed in neuronal cells. ENO1 is also known as enolase alpha and as non-neuronal enolase. The third enolase, ENO3 or enolase beta, is expressed in muscle cells. Since neurons require a great deal of energy, they are very rich in glycolytic enzymes such a GAPDH and NSE. Antibodies to this protein are therefore useful to identify neuronal cell bodies, developing neuronal lineage and neuroendocrine cells. Release of NSE from damaged neurons into CSF and blood has also been used as a biomarker of neuronal injury. Anti-neuron specific enolase (NSE) antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.
- Versandbedingungen:
- Dry Ice