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100-401-D29

DsbA-L Antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
100-401-D29
Zusätzliche Namen:
Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, Glutathione S-transferase subunit 13, Disulfide-bond-A oxidoreductase-like protein, DsbA-L|Gstk1
Anwendung:
ELISA, IHC, WB
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Mouse
Lagerbedingungen:
Please refer to datasheet
Hersteller:
Rockland Inc
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Immunogen:
Anti-DsbA-L Antibody was produced in rabbit by repeated immunizations with full length recombinant mouse DsbA-L protein
Format:
Antiserum
Uniprot:
Q9DCM2
Synonyme:
0610025I19Rik;AW260476;Dsb;DsbA-L;glutathione S-transferase class kappa;glutathione S-transferase kappa 1;glutathione S-transferase subunit 13;GST 13-13;GST class-kappa;GSTK1-1;mGSTK1
Weitere Details:
DsbA-L Antibody detects Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) which is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution. Overexpression of DsbA-L promotes adiponectin multimerization while suppressing DsbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis. Anti-DsbA-L Antibody is ideal for investigators involved in Cell Signaling and Cell Metabolism.
Versandbedingungen:
Dry Ice