100-401-A17
CDC20 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 100-401-A17
- Zusätzliche Namen:
- CDC20|rabbit anti-Cdc20 Antibody, CDC antibody, CDC20 cell division cycle 20 homolog antibody, CDC20A antibody, Cell division cycle 20 antibody, Cell division cycle 20 homolog antibody, Cell division cycle protein 20 homolog antibody, fizzy antibody, MGC102824 antibody, p55CDC antibody
- Anwendung:
- ELISA, IHC, WB, IP
- Konzentration:
- 85 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Immunogen:
- This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 486-499 of Human CDC20 (fizzy) (C-terminal) coupled to KLH.
- Format:
- Antiserum
- Uniprot:
- Q12834
- Synonyme:
- bA276H19.3;CDC20 cell division cycle 20 homolog;CDC20A;cell division cycle 20 homolog;cell division cycle protein 20 homolog;fizzy homolog;p55CDC
- Weitere Details:
- CDC20, also known as fizzy, Cell division cycle protein 20 homolog, and p55CDC is required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. CDC20 is regulated by MAD2L1. In metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The phosphorylated form of CDC20 interacts with APC/C. Synthesis is initiated at G1/S, protein level peaks in M phase and protein is abruptly degraded at M/G1 transition.
- Versandbedingungen:
- Dry Ice