100-401-A09
DDB1 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 100-401-A09
- Zusätzliche Namen:
- DDB1|rabbit anti-Anti-p127-DDB1 antibody, Damage specific DNA binding protein 1 antibody, DDB 1 antibody, DDB p127 subunit antibody, DDBa antibody, DNA damage binding protein 1 antibody, UV damaged DNA binding factor antibody
- Anwendung:
- ELISA, IHC, WB, IP
- Konzentration:
- 85 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Immunogen:
- DDB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 198-213 of Human DDB1 (internal) coupled to KLH.
- Format:
- Antiserum
- Uniprot:
- Q16531
- Synonyme:
- damage-specific DNA binding protein 1, 127kDa;Damage-specific DNA-binding protein 1;DDB p127 subunit;DDBA;DNA damage-binding protein 1;DNA damage-binding protein a;HBV X-associated protein 1;UV-damaged DNA-binding factor;UV-damaged DNA-binding protein 1;UV-DDB 1;UV-DDB1;WHIKERS;XAP-1;XAP1;xeroderma pigmentosum group E-complementing protein;XPCE;XPE;XPE-BF;XPE-binding factor
- Weitere Details:
- DDB1 is also known as damage-specific DNA binding protein 1, DDB p127 subunit, DDBa, UV-damaged DNA-binding protein 1, UV-DDB 1, Xeroderma pigmentosum group E complementing protein, XPCe, X-associated protein 1 and XAP-1. The DDB1 gene encodes the large subunit (p127) of DNA damage-binding protein, which is a heterodimer, composed of a large and a small subunit (p48 DDB2). This nuclear protein functions in nucleotide-excision repair resulting from UV-damaged DNA by binding to pyrimidine dimers. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). XP-E is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. DDB1 antibody is involved in Epigenetic and Cancer / DNA Damage research.
- Versandbedingungen:
- Dry Ice