100-401-A06
Cul7 Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 100-401-A06
- Zusätzliche Namen:
- CUL7|rabbit anti-Cul7 Antibody, rabbit anti-Cullin7 antibody, CUL, Cullin
- Anwendung:
- ELISA, IHC, WB, IP
- Konzentration:
- 85 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Immunogen:
- This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-Terminus region near amino acids 1675-1698 of Human Cul7 coupled to KLH.
- Format:
- Antiserum
- Uniprot:
- Q14999
- Synonyme:
- 3M1;CUL-7;cullin-7;dJ20C7.5;KIAA0076
- Weitere Details:
- Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 7 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 7 seems to be involved proteosomal degradation of proteins involved in endothelial proliferation and/or differentiation. Cullin 7 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1, FBXW8 and GLMN isoform 1. Cullin 7 interacts with a complex of SKP1 and FBXW8, but not with SKP1 alone.
- Versandbedingungen:
- Dry Ice