100-101-207
Alpha-2-Macroglobulin Antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 100-101-207
- Zusätzliche Namen:
- A2M|goat anti-Alpha-2-Macroglobulin Antibody, goat anti-A2M antibody, Alpha 2 M antibody, Alpha 2M antibody, CPAMD5 antibody, DKFZp779B086 antibody, FWP007 antibody, S863 7 antibody, Alpha-2-M, PZP-like alpha-2-macroglobulin domain-containing protein 5
- Anwendung:
- ELISA, IHC, WB
- Konzentration:
- 82 mg/ml
- Physischer Zustand:
- Lyophilized
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Rockland Inc
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- Immunogen:
- a2-Macroglobulin [Human Plasma]
- Formulierung:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Format:
- Antiserum
- Uniprot:
- P01023
- Synonyme:
- A2MD;alpha-2-M;alpha-2-macroglobulin;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5;CPAMD5;FWP007;S863-7
- Weitere Details:
- Alpha-2-Macroglobulin is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. Alpha-2-Macroglobulin has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
- Versandbedingungen:
- Ambient