010-001-C21
MIP-3 beta Mouse Recombinant Protein
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 010-001-C21
- Zusätzliche Namen:
- C-C motif chemokine 19, Small-inducible cytokine A19, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, ELC|Ccl19
- Anwendung:
- SDS-PAGE
- Konzentration:
- 0.1 ug/ml
- Physischer Zustand:
- Lyophilized
- Reinheit:
- >98%
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Buffer:
- 0.1% Trifluoroacetic acid
- Immunogen:
- Ccl19
- Formulierung:
- 0.1% Trifluoroacetic acid
- Spezies:
- Mouse
- Uniprot:
- O70460
- Synonyme:
- C-C motif chemokine 19;Ccl19;chemokine CCL19;CKb11;EBI-1 ligand chemokine;EBI1 ligand chemokine;EBV-induced molecule 1 ligand chemokine;ELC;epstein-Barr virus-induced molecule 1 ligand chemokine;exodus;exodus-3;Gm2023;MIP3B;Scya;Scya19;small-inducible cytokine A19
- Weitere Details:
- Macrophage Inflammatory Protein-3-beta (CCL 19, of the intercrine beta chemokine CC family) is an important secreted chemoattractant for dendritic cells, antigen-engaged B-cells, and effector-memory T-cells, signaling through the CCR7 receptor. It may play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. MIP-3B Beta specifically binds to chemokine receptor CCR7. MIP-3B Beta is strongly chemotactic for naive CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory CD4 T-cells. There is significant expression in dendritic cells in mesenteric and peripheral lymph nodes, and in spleen (T-cell zone or periarteriolar lymphatic sheath) and Peyer patches, but low expression in thymus. Recombinant mouse MIP-3-beta is a polypeptide chain consisting of 83 amino acids with a molecular weight of 9,200 Daltons.
- Versandbedingungen:
- Ambient