010-001-B32
IL-17A Mouse Recombinant Protein
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 010-001-B32
- Zusätzliche Namen:
- Il17a|Interleukin-17A cytokine, IL-17A, IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8
- Anwendung:
- SDS-PAGE
- Konzentration:
- 0.1 mg/ml
- Physischer Zustand:
- Lyophilized
- Reinheit:
- >98%
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Buffer:
- 0.1% Trifluoroacetic acid
- Immunogen:
- Il17a
- Formulierung:
- 0.1% Trifluoroacetic acid
- Spezies:
- Mouse
- Uniprot:
- Q62386
- Synonyme:
- Ctl;Ctla;Ctla-8;Ctla8;cytotoxic T-lymphocyte-associated antigen 8;Il;IL-;IL-17;IL-17A;Il17;interleukin-17A
- Weitere Details:
- Mouse Interleukin-17A (IL-17A), also known as CTLA-8, is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Mouse IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and mouse IL-17A. Recombinant mouse IL-17A produced in E.coli is a non-glycosylated disulfide-joined homodimer having a molecular mass of 30.0 kDa.
- Versandbedingungen:
- Ambient