009-001-310
rHuman IL-6 Protein
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 009-001-310
- Zusätzliche Namen:
- IL6|Interleukin-6 cytokine, IL-6, B-cell stimulatory factor 2, BSF-2, Interferon beta-2, IFN-beta-2, Hybridoma growth factor, CTL differentiation factor, CDF, Interleukin HP-1
- Anwendung:
- SDS-PAGE
- Konzentration:
- 0.1 mg/ml
- Physischer Zustand:
- Lyophilized
- Reinheit:
- >95%
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Buffer:
- 0.01 M Sodium Phosphate
- Immunogen:
- IL6
- Formulierung:
- 0.01 M Sodium Phosphate, pH 7.5
- Spezies:
- Human
- Uniprot:
- P05231
- Synonyme:
- B-cell differentiation factor;B-cell stimulatory factor 2;BSF-2;BSF2;CDF;CTL differentiation factor;HGF;HSF;hybridoma growth factor;IFN-beta-2;IFNB2;IL-6;interferon beta-2;interleukin BSF-2;interleukin-6
- Weitere Details:
- Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contains four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist: the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha-helix is important to the biological activity of the molecule. Interleukin (IL)-6 is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro. Recombinant Human IL-6 produced in E.coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 21,000 Daltons.
- Versandbedingungen:
- Ambient