ErpN/OspE Control Protein

Eine Lieferung in diese Region ist nicht möglich.

SKU:: 000-001-C10
Zusätzliche Namen:: erpN, BB_L39|ErpN, ErpA, outer surface protein E, Borrelia burgdorferi OspE, ospE/F-Related Protein N, control protein
Anwendung:: ELISA, SDS-PAGE, WB, Functional Assay
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Reinheit:: >90%
Lagerbedingungen:: Please refer to datasheet
Hersteller:: Rockland Inc
Buffer:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
Immunogen:: erpN, BB_L39
Formulierung:: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Spezies:: Bacteria
Synonyme:: BB_L39;BB_RS07085;plasminogen-binding protein ErpA
Weitere Details:: ErpN (OspE/F-Related Protein N), is from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. Erp proteins from Borrelia burgdorferi are postulated to be lipoproteins, based on their predicted amino acid sequences. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Several studies have demonstrated that infected humans and animals produce antibodies directed against Erp proteins within the first 2-4 weeks of infection, indicative of Erp synthesis during the initial stages of vertebrate infection. It is postulated that surface-exposed Erp proteins could facilitate interactions with host tissues during the establishment of vertebrate infection. Lyme disease proteins are ideal for researchers interested in immunology, neurology, and rheumatology, coinfections, autoimmune, and neurodegenerative diseases.

Versandbedingungen:: Dry Ice