000-000-260
AKT/PKBa Substrate
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- 000-000-260
- Zusätzliche Namen:
- AKT1|AKT1, serine/threonine kinase, apoptosis inhibitor substrate peptides, blocking peptide, control peptide
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Lyophilized
- Reinheit:
- >98%
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Rockland Inc
- Immunogen:
- AKT1
- Weitere Details:
- Akt is a serine/threonine kinase that enhances cell proliferation and inhibits apoptosis when activated. Akt associates with PI(3,4,5)P3) at the cell membrane through its pleckstrin homology domain and is activated through phosphorylation. 3-Phosphoinositide-dependent kinase-1 (PDK1) has been shown to first phosphorylate Akt at Thr308, then a second kinase phosphorylates Akt at position Ser473. In turn, Akt phosphorylates a host of proteins including the proapoptotic proteins BAD and pro-caspase-9, GSK3, p21WAF1, MDM2, and the forkhead (FKHR) family of transcription factors.
- Versandbedingungen:
- Ambient