GTX89960
SET antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89960
- Zusätzliche Namen:
- SET nuclear proto-oncogene , 2PP2A , I2PP2A , IGAAD , IPP2A2 , MRD58 , PHAPII , TAF-I , TAF-IBETA
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence SAPAAKVSKKELNS-C, from the N Terminus of the protein sequence according to NP_003002.2.
- Uniprot:
- Q01105
- Synonyme:
- 2PP2A;chromatin remodelling factor;HLA-DR-associated protein II;I2PP2A;IGAAD;inhibitor of granzyme A-activated DNase;inhibitor-2 of protein phosphatase-2A;IPP2A2;MRD58;PHAPII;phosphatase 2A inhibitor I2PP2A;protein phosphatase type 2A inhibitor;protein SET;SET nuclear oncogene;SET translocation (myeloid leukemia-associated);TAF-I;TAF-IBETA;Template-activating factor I;Template-Activating Factor-I, chromatin remodelling factor
- Weitere Details:
- The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Versandbedingungen:
- Blue Ice