GTX89889
Rad51C antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89889
- Zusätzliche Namen:
- RAD51 paralog C , BROVCA3 , FANCO , R51H3 , RAD51L2
- Anwendung:
- WB
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence RGKTFRFEMQRDL-C, from the N Terminus of the protein sequence according to NP_002867.1; NP_478123.1.
- Uniprot:
- O43502
- Synonyme:
- BROVCA3;DNA repair protein RAD51 homolog 3;FANCO;R51H3;RAD51 homolog C;RAD51-like protein 2;RAD51L2;yeast RAD51 homolog 3
- Weitere Details:
- This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Versandbedingungen:
- Blue Ice