GTX89789
Transgelin antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89789
- Zusätzliche Namen:
- transgelin , SM22 , SM22-alpha , SMCC , TAGLN1 , WS3-10
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human, Mouse
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-MTGYGRPRQIIS, from the C Terminus of the protein sequence according to NP_003177.2.
- Uniprot:
- Q01995
- Synonyme:
- 22 kDa actin-binding protein;epididymis secretory sperm binding protein;Protein WS3-10;SM22;SM22-alpha;SMCC;smooth muscle protein 22-alpha;TAGLN1;transgelin;transgelin variant 2;WS3-10
- Weitere Details:
- This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice