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GTX89716-PEP

PI3 kinase C2 alpha blocking peptide

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX89716-PEP
Zusätzliche Namen:
Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha , Cpk , Pi3-K-C2(Alpha) , Pi3-K-C2A , Pi3K-C2-Alpha , Pi3K-C2Alpha , Pik3C2A
Physischer Zustand:
Lyophilized
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Buffer:
Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Spezies:
Human
Synonyme:
C2-containing phosphatidylinositol kinase;CPK;OCSKD;phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha;phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha;phosphoinositide 3-kinase-C2-alpha;phosphoinositide-3-kinase, class 2, alpha polypeptide;PI3-K-C2(ALPHA);PI3-K-C2A;PI3K-C2-alpha;PI3K-C2alpha;ptdIns-3-kinase C2 subunit alpha
Weitere Details:
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice