GTX89656-PEP
LXR alpha / LXR beta blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89656-PEP
- Zusätzliche Namen:
- LXRA blocking peptide , NR1H3 blocking peptide , LXR A blocking peptide , RLD1 blocking peptide
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- nuclear receptor subfamily 1 group H member 3
- Spezies:
- Human
- Synonyme:
- liver X nuclear receptor alpha variant 1;LXR-a;LXRA;oxysterols receptor LXR-alpha;RLD-1
- Weitere Details:
- The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Versandbedingungen:
- Blue Ice