GTX89491
SDHB antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89491
- Zusätzliche Namen:
- succinate dehydrogenase complex iron sulfur subunit B , CWS2 , IP , PGL4 , SDH , SDH1 , SDH2 , SDHIP
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-ATYKEKKASV, from the C Terminus of the protein sequence according to NP_002991.2.
- Uniprot:
- P21912
- Synonyme:
- CWS2;IP;iron-sulfur subunit of complex II;MC2DN4;PGL4;SDH;SDH1;SDH2;SDHIP;succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
- Weitere Details:
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice