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  2. Polyclonal

GTX89432

HP1 alpha antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX89432
Zusätzliche Namen:
chromobox 5 , HEL25 , HP1 , HP1A
Anwendung:
Flow Cytometry, WB, IHC-P
Konzentration:
0.50 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Ammonium Sulfate Precipitated; Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Goat
Reaktivitäten:
Human, Mouse
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:
Peptide with sequence C-NKRKSNFSNSADDIK, from the internal region of the protein sequence according to NP_036249.1; NP_001120793.1; NP_001120794.1.
Uniprot:
P45973
Synonyme:
antigen p25;chromobox homolog 5 (HP1 alpha homolog, Drosophila);chromobox protein homolog 5;epididymis luminal protein 25;HEL25;heterochromatin protein 1 homolog alpha;heterochromatin protein 1-alpha;HP1;HP1 alpha homolog;HP1-ALPHA;HP1A;HP1Hs alpha
Weitere Details:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice