GTX89392-PEP
p27 Kip1 (internal) blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX89392-PEP
- Zusätzliche Namen:
- Cyclin Dependent Kinase Inhibitor 1B , Cdkn4 , Kip1 , Men1B , Men4 , P27Kip1 , Cdkn1B
- Physischer Zustand:
- Lyophilized
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- cyclin-dependent kinase inhibitor 1B (p27, Kip1)
- Spezies:
- Human
- Synonyme:
- CDKN4;cyclin-dependent kinase inhibitor 1B;cyclin-dependent kinase inhibitor 1B (p27, Kip1);KIP1;MEN1B;MEN4;P27KIP1
- Weitere Details:
- This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
- Versandbedingungen:
- Blue Ice